PROMOTING TOURISM IN DEVELOPING ECONOMIES: CHALLENGES AND PROSPECTS.


Mutations in Epigenetic Modifiers in Myeloid Malignancies and the Prospect of Novel Epigenetic-Targeted Therapy

In the recent years, the discovery of a series of mutations in patients with myeloid malignancies has provided insight into the pathogenesis of myelodysplastic syndromes (MDSs), myeloproliferative neoplasms (MPNs), and acute myeloid leukemia (AML).Among these alterations have been mutations in genes, such as IDH1/2, TET2, DNMT3A, and EZH2, Placemat

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Scheme of High Speed Contact Rail System for 120 km/h and above

Objective In order to meet the demand for traction current collection in rail transit at the speed of 120 km/h and above, the research on high speed contact rail system is conducted and a complete optimization scheme is proposed.Method Based on the analysis of the influencing factors of shoe rail current collection, the idea about optimizing the qu

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A study of predictors of retention to naltrexone maintenance therapy in patients with opioid use disorder: a prospective study

Abstract Objectives Naltrexone prophylaxis is a well-established treatment for opioid use disorder.Our study aimed to track patients on naltrexone and investigate the factors predictive of retention.Materials and methods The study comprised 100 participants initiated on naltrexone, who underwent a 12-week follow-up.We analyzed a range of socio-demo

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